Organizers: Yoonsuck Choe, John Keyser, and Louise C. Abbott
Brain Networks Laboratory, Texas A&M University
Synopsis: Rapid advances in high-throughput, high-volume 3D microscopy
technology is enabling the acquisition of neuronal-level data at the scale of
whole small animal organs such as the mouse brain. Techniques that allow 3D
molecular imaging and ultra high-resolution electron microscopy imaging
provide a complementary perspective, where detailed local circuit function
can be investigated.
These microscopy technologies, together with
high-performance computing power becoming available are enabling
a data-driven, multi-scale modeling and simulation of large-scale neuronal
circuits (such as the complete connectome of the mouse). This workshop will
give a timely update on this burgeoning field and provide a forum for intensive
discussion to shape the immediate and future direction of data-driven
computational modeling and simulation of the brain.
Acknowledgments:
3Scan
Organization for Computational Neuroscience
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Program:
This will be a day-long workshop, with the
program consisting of the talks listed below, plus an hour-long
panel discussion where everyone is encouraged to participate.
Confirmed talks : Abstracts are now online. First authors will give the presentation.
- [9:00am] Introduction
[PDF slides]
- [9:10am]
Louise C. Abbott, David Mayerich, Jaerock Kwon*, and Yoonsuck Choe
(Texas A&M University, *Kettering University)
High-throughput imaging of whole mouse brain using the
Knife-Edge Scanning Microscope
[Abstract]
- [9:35am]
Kenneth J. Hayworth, Narayanan Kasthuri, Richard Schalek, Juan C. Tapia,
Jeff Lichtman (Harvard University)
Large Volume Neural Circuit Reconstruction Using the Tape
to SEM Process
[Abstract]
- [10:00am]
Daniel Berger and H. Sebastian Seung (MIT)
Semi-automatic SEM imaging and analysis of neuronal connectivity using ATLUM/ATUM slice stacks
[Abstract]
- [10:25am] Coffee break
- [10:35am]
Brad Busse, Kristina Micheva, and Stephen J. Smith (Stanford University)
Large scale synaptic analysis with Array Tomography
[Abstract]
- [11:00am]
Pablo Blinder1, Philbert S. Tsai1,
John Kaufhold2, and David Kleinfeld1
(University of California, San Diego1 and SAIC2)
Reconstruction of the cortical vascular network in mouse
[Abstract]
- [11:25am]
Chris Bjornsson and Badri Roysam (RPI)
Mapping the Glio-vascular Infrastructure of Brain Tissue
[Abstract]
- [12:15pm] Lunch break
- [1:30pm]
David Mayerich1, Yoonsuck Choe2, and John Keyser2 (1University of Illinois,
Urbana-Champaign and 2Texas A&M University)
Segmentation and
Visualization of High-Throughput Microscopy Datasets
[Abstract]
- [1:55pm]
Randal Koene (Fatronic Tecnalia Foundation, San Sebastian, Spain)
Using new in-vivo techniques to add function to
reconstructions from high-throughput micrsocopy
[Abstract]
- [2:20pm]
Andrew Duchowski (Clemson University)
Eye-tracking technology and its potential
application to tracing and validation of microscopy data
[Abstract]
- [2:45pm]
Todd Huffman (3Scan) and Peter Eckersley (Electronic Freedom Foundation)
Large-scale, collaborative scanning, and the role of
commercialization (tentative title)
[Abstract]
- [3:10pm] Coffee break
- [3:35pm]
Yoonsuck Choe (Texas A&M University) and Jaerock Kwon (Kettering
University)
Open issues in high-fidelity simulation of the connectome
[Abstract] [PDF slides]
- [4:00pm] Panel
[PDF slides]
* First author will give the presentation. Some titles are tentative.
Schedule summary:
start duration
09:00:00 AM 00:10 Intro
09:10:00 AM 00:25 Abbott
09:35:00 AM 00:25 Hayworth
10:00:00 AM 00:25 Berger
10:25:00 AM 00:10 > coffee break
10:35:00 AM 00:25 Busse
11:00:00 AM 00:25 Blinder
11:25:00 AM 00:50 Bjornsson keynote
12:15:00 PM 01:15 > lunch
01:30:00 PM 00:25 Mayerich
01:55:00 PM 00:25 Koene
02:20:00 PM 00:25 Duchowski
02:45:00 PM 00:25 Huffman
03:10:00 PM 00:25 > coffee break
03:35:00 PM 00:25 Choe
04:00:00 PM 01:00 > Panel
05:00:00 PM
Sponsors:
- 3Scan
- Organization for Computational Neuroscience (OCNS)
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