SClassify is a supervised protein family classification algorithm that overcomes the problems of existing supervised and unsupervised algorithms and achieves much improved accuracy. It can assign proteins to existing families in databases, and by taking into account similarities between the unclassified proteins, can assign them to new families.
The SClassify source code, including sample input and output files, can be compiled under the Unix/Linux/Windows(Cygwin) environment. The following steps will create a directory called sclassify. Detailed usage of SClassify is provided in a README file.
Yi G., Thon M.R. and Sze S.-H. (2012) Supervised protein family classification and new family construction. Journal of Computational Biology, 19, 957-967.